Vitamin B5 – Pantothenic Acid

In Greek 'pantos' means 'everywhere'. Utilised in the manufacture of coenzyme A (CoA) and acyl carrier protein (ACP), conversion of fats and CHO for energy production and the manufacture of adrenal hormones and red blood cells. (Murray 2001)

Deficiency Signs and Symptoms
Fatigue, burning foot syndrome, numbness or shooting pain.

Naturopathic Dosage Range
Will vary depending on what is being treated, adaquate maintenance dose is 100 mg per dose

Main Uses
Adrenal support – known as the anti stress vitamin.
Rheumatoid arthritis – often there are lower levels the worse the symptoms are, helps to alleviation of pain.
High cholesterol and triglycerides – reduces levels, and lipid lowering effect in diabetics.

Safety
No side effects reported

Vitamin B3 – Niacin

Can be converted from the amino acid tryptophan. Involved in energy production, fat, cholesterol and carbohydrate metabolism and the manufacture of compounds such as sex and adrenal hormones.

Deficiency Signs and Symptoms
Pellagra – dermatitis, dementia, diarrhoea, death

Naturopathic Dose
Maintenance 100 mg taken with meals.

Main Uses

Energy production, regulates blood sugar, antioxidant, liver detox, reduces cholesterol.
Lowers blood lipids – niacin works better, in some instances, than cholesterol lowering pharmaceuticals.
Diabetes – used under supervision instead of autoimmune drugs (prednisone), safer and effectivAe.
Arthritis – rheumatoid and osteoarthritis, high dose have been proven useful.

Safety
Skin flushing 20 – 30 min after, irritating factor not dangerous.
Gastric irritation, nausea, liver damage – avoid time release tablets.
Caution in liver damage, or elevated liver enzymes, gout or peptic ulcer.
In diabetes use under supervision of a practitioner because of impaired glucose tolerance.
Liver function tests and cholesterol tests advised during high doses.

Vitamin B2 – Riboflavin

Excess B2 results in yellow-green urine. involved in energy production.

Deficiency Signs and Symptoms
Cracking lips, sores in corner of mouth, inflamed tongue, visual disturbances – sensitive to light, loss of visual acuity, cataracts, burning and itching eyes, lips, mouth, tongue. Disorders of mucous membranes. Anaemia and seborrhoeic dermatitis.
 
naturopathic Dose
Maintenance 5 – 10 mg daily
   
Main Uses

Migraine – prevention, based on theory thatmigraines are caused by reduced energy production within mitochondria of cerebral blood vessels.
Cataracts – reduced generation of glutathione enhances formation
Sickle cell anaemia – increases iron status and glutathione levels.

Safety
No toxicity.

Vitamin B1 – Thiamin

Deficiency Signs and Symptoms
Beriberi – mental confusion, muscle wasting (dry), fluid retention (wet), high Bp, difficulty walking, heart disturbances. Can result from eating white rice rather than whole grain.
Mild deficiency – fatigue, depression, pins and needles or numbness in legs, constipation.
In alcoholics with thiamin deficiency = Wernicke-Korsakoff syndrome.

Main Uses
Prevent deficiency in diabetes, Crohn’s dx, MS, neurological diseases.
Prevent and treat impaired mental function in elderly, in Alzheimer’s it is essential for energy production in brain, severe deficiency causes psychosis. Mimics NT acetylcholine (memory),which is often low in Alzeimer’s. (Murray 2001)
Epileptics on Dilantin (phenytoin) – improves mental function.

Naturopathic Dose

100 mg daily

Cautions
None

Inositol

Is an unofficial B vitamin which functions closely with choline. It is a primary component of cell membranes, as phosphatidylinositol. (Haas 1999)

Food Sources
Citrus fruit, whole grains, nuts, seeds, legumes. Fibre component of phytic acid (inositol phosphate). Intestinal bacteria releases inositol from phytic acid.

Main Uses
Liver disorders (100 – 500 mg)
Depression and panic attacks – used in serotonin and acetylcholine, depressed patients show low levels of inositol in cerebrospinal fluid, shown to reduce depression and panic.
Diabetes – neuropathy, decreased nerve function because of loss of inositol from nerve cell.